an acetylated type sodium hyaluronate,Sodium Acetylated Hyaluronate

Sodium Acetylated Hyaluronate

Short Description:

Cosmate®AcHA,Sodium Acetylated Hyaluronate (AcHA), is a specialty HA derivative which is synthesized from the Natural Moisturizing Factor Sodium Hyaluronate (HA) by acetylation reaction. The hydroxyl group of HA is partially replaced with acetyl group. It owns both lipophilic and hydrophilic properties. This helps to promote high affinity and adsorption properties for the skin.


  • Trade Name: Cosmate®AcHA
  • Product Name: Sodium Acetylated Hyaluronate
  • INCI Name: Sodium Acetylated Hyaluronate
  • Molecular Formula: (C14H16O11NNaR4)n R=H or CH3CO
  • CAS No.: 158254-23-0
  • Product Detail

    Why Zhonghe Fountain

    Product Tags

    Sodium Acetylated Hyaluronate is a ground-breaking skincare ingredient set to become the cornerstone of your beauty regime. Also known as Sodium Acetylated Hyaluronate (AcHA), Sodium Acetylated Hyaluronate is a modified NMF Sodium Hyaluronate (HA). Sophisticated acetylation processes replace the hydroxyl group of HA partially with an acetyl group, endowing the compound with both lipophilic and hydrophilic properties. The dual property is responsible for bulk-fluidity and adsorption power, thereby providing maximum hydration and nourishment to the skin. This ultimate innovation Sodium Acetylated Hyaluronatewill reshape your skincare routine with excellent water-holding capability and skin compatibility.

    Sodium Acetylated Hyaluronate is the latest in the line of innovations that are transforming skincare ingredients for beautification. Sodium Acetylated Hyaluronate, an exclusive derivative of Sodium Hyaluronate, is designed to deliver both hydrophilic and lipophilic benefits through the acetylation method. Reportedly, this amazing active has a good affinity to skin and high efficacy in hydration. Immediate softening of the stratum corneum, elasticity improvement, and texture enhancement are the other things. Refreshing and non-greasy, Sodium Acetylated Hyaluronate is suitable in lotions, masks, and essences, pampering your skin the way they deserve. Sodium Acetylated Hyaluronate takes skincare into the next level.

    Cosmate®AcHA,Sodium Acetylated Hyaluronate with below outstanding advantages:

    High Skin affinity:Sodium Acetylated Hyaluronate hydrophilic and fat-friendly nature give it a special affinity with skin’s cuticles.The high skin affinity of AcHA makes it more evently and closely adsorbed on the surface of the skin,even after rinsing with water.

    Strong Moisture Retention:Sodium Acetylated Hyaluronate can firmly adhere to the surface of the skin,reduce the loss of  water on the skin surface,and increase the content of moisture of skin.It also can quickly penetrate into the stratum corneum,combine with the water in the stratum corneum,and hydrate to soften the stratum corneum.AcHA internal and external synergistic effect,play an efficient and lasting moisturing effect,increase skin water content,improve skin rough,dry state,make skin full and moist.

    Sodium Acetylated Hyaluronate is a highly advanced derivative of hyaluronic acid, modified through acetylation to enhance its stability, penetration, and moisturizing properties. This innovative ingredient is widely used in skincare formulations for its ability to deliver deep hydration, improve skin elasticity, and provide long-lasting anti-aging benefits.

    Key Functions :

    1. Deep Hydration: Sodium Acetylated Hyaluronate has an exceptional ability to attract and retain moisture, providing intense hydration to the skin.
    2. Enhanced Penetration: The acetylation modification allows it to penetrate deeper into the skin layers, ensuring long-lasting moisturizing effects.
    3. Anti-Aging: By improving skin elasticity and reducing the appearance of fine lines and wrinkles, it helps maintain a youthful and plump complexion.
    4. Barrier Repair: It strengthens the skin’s natural moisture barrier, preventing water loss and protecting against environmental stressors.
    5. Soothing & Calming: It helps soothe irritated or sensitive skin, reducing redness and discomfort.

    Mechanism of Action:
    Sodium Acetylated Hyaluronate works by forming a hydration layer on the skin’s surface and penetrating into the deeper layers of the epidermis. Its acetylated structure enhances its stability and ability to bind water, ensuring optimal hydration and skin protection.

    Advantages :

    • High Purity & Performance: Our Sodium Acetylated Hyaluronate is rigorously tested to ensure superior quality and efficacy.
    • Versatility: Suitable for a wide range of products, including serums, creams, masks, and lotions.
    • Gentle & Safe: Suitable for all skin types, including sensitive skin, and free from harmful additives.
    • Proven Efficacy: Backed by scientific research, it delivers visible results in improving skin hydration and texture.
    • Synergistic Effects: Works well with other active ingredients, enhancing their stability and effectiveness.

    Applications:

    • Moisturizers: Provides deep hydration and improves skin elasticity.
    • Anti-Aging Products: Reduces fine lines and wrinkles while promoting a youthful complexion.
    • Sensitive Skin Care: Calms irritation and strengthens the skin barrier.
    • Masks: Offers intensive hydration and soothing effects.

    R (1)

     Technical Parameters:

    Appearance White to yellowish granule or powder
    Acetyl Content 23.0~29.0%
    Transparency(0.5%,80% Ethnol) 99% min.
    pH(0.1% in water solution) 5.0~7.0
    Intrinsic Vicosity 0.50~2.80 dL/g
    Protein 0.1%max.
    Loss on Drying 10% max.
    Heavy Metals(As Pb) 20 ppm max.
    Residue on Ignition 11.0~16.0%
    Total Bacteria Count 100 cfu/g max.
    Molds &Yeasts 50 cfu/g max.
    Staphylococcus Aureus Negative
    Pseudomonas Aeruginosa Negative

     Applications:

    *Moisturizing

    *Skin Reparing

    *Anti-Aging


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