Anti-aging Silybum marianum extract Silymarin

Silymarin

Short Description:

Cosmate®SM, Silymarin refers to a group of flavonoid antioxidants that naturally occur in milk thistle seeds (used historically as an antidote for mushroom poisoning). The components of Silymarin are Silybin, Silibinin, Silydianin, and Silychristin. These compounds protect and treat the skin from oxidative stress caused by ultraviolet radiation. Cosmate®SM, Silymarin also has powerful antioxidant properties that prolong cell life. Cosmate®SM, Silymarin can prevents UVA and UVB exposure damage. It is also being studied for its ability to inhibit tyrosinase (a critical enzyme for melanin synthesis) and hyperpigmentation. In wound healing and anti-aging, Cosmate®SM,Silymarin can inhibit the production of inflammation-driving cytokines and oxidative enzymes. It can also increase collagen and glycosaminoglycans (GAGs) production, promoting a broad spectrum of cosmetic benefits. This makes the compound great in antioxidant serums or as a valuable ingredient in sunscreens.

Trade Name: Cosmate®SM

Product name: Silymarin

INCI Name: Silybum marianum extract

Molecular Formula: C25H22O10

CAS No.: 65666-07-1

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Cosmate®SM Silymarin, a premium natural flavonoid lignan compound derived from the dried fruit of the Milk Thistle plant (Asteraceae). This powerful extract contains four key components: silybin, isosilybin, silybin, and silymarin. Known for its health benefits, Cosmate®SM Silymarin displays versatility in its solubility profile – it is readily soluble in acetone, ethyl acetate, methanol, and ethanol, but slightly soluble in chloroform and insoluble in water. Suitable for a variety of uses, Cosmate®SM Silymarin is a valuable ingredient for those seeking a natural, effective, and high-quality supplement.

For over 2,000 years Silybum marianum has been working its magic. Ancient Greeks and Romans used Milk Thistle against the venom of snake bites, today Milk Thistle’s phyto-compounds are translated through cosmetics, body products, serums and haircare. The NE Milk Thistle Cellular Extract’s phyto-compounds may be considered for numerous skin conditions, hydration, pollution defense, fine lines, wrinkles and more. The NE Milk Thistle Cellular Extract delivers the highest concentration of silymarin, believed to have powerful healing powers, as well as tryptophan, and amino and phenolic acids.

Cosmate®SM, Silymarin 80% – a powerful natural solution for liver health. This high-quality extract is derived from milk thistle and is standardized to contain 80% silymarin, a potent blend of flavonoids including silymarin, silymarin, and silymarin. Known for its outstanding antioxidant properties, silymarin helps protect liver cells from damage, supports the detoxification process, and promotes overall liver function. Trusted by health enthusiasts and professionals alike, Cosmate®SM, Silymarin 80% is your go-to supplement for maintaining liver health and optimal health. Discover the benefits of this extraordinary herb and support your liver health the natural way.

Technical Parameters:

Appearance	Amorphous Powder
Colour	Yellow to Yellowish-Brown
Odour	Slight, Specific
Solubility
- in Water	Practically Insoluble
- in Methanol and Acetone	Soluble
Identification	Thin-Layer Chromatographic Identification Test HPLC Identification Test
Sulphated Ash	NMT 0.5%
Heavy metals	NMT 10 PPM
- Lead	NMT 2.0 PPM
- Cadmium	NMT 1.0 PPM
- Mercury	NMT 0.1 PPM
- Arsenic	NMT 1.0 PPM
Loss On Drying (2 Hours 105 ℃)	NMT 5.0%
Powder size
Mesh 80	NLT100%
Assay of Silymarin (UV test, per cent, Standard in House)	Min. 80%
Residual Solvents
- N-hexane	NMT 290 PPM
- Acetone	NMT 5000 PPM
- Ethanol	NMT 5000 PPM
Pesticide Residues	USP43<561>
Microbiological Quality (Total viable aerobic count)
- Bacteria, CFU/g, not more than	10³
- Moulds and yeasts, CFU/g, not more than	10²
- E.coli, Salmonella, S. aureus, CFU/g	Absence