Cosmate®SM, Silymarin, a natural flavonoid lignan compound, is extracted from the dried fruit of milk thistle, a plant in the asteraceae family. Its main components are silybin, isosilybin, silydianin and silychristin. Cosmate®SM,Silymarin is insoluble in water, easily soluble in acetone, ethyl acetate, methanol ethanol, slightly soluble in chloroform.
For over 2,000 years Silybum marianum has been working its magic. Ancient Greeks and Romans used Milk Thistle against the venom of snake bites, today Milk Thistle’s phyto-compounds are translated through cosmetics, body products, serums and haircare. The NE Milk Thistle Cellular Extract’s phyto-compounds may be considered for numerous skin conditions, hydration, pollution defense, fine lines, wrinkles and more. The NE Milk Thistle Cellular Extract delivers the highest concentration of silymarin, believed to have powerful healing powers, as well as tryptophan, and amino and phenolic acids.
Cosmate®SM, Silymarin 80% is well known as a potent herb for liver disorders. The active ingredients in milk thistle are flavonoids comprised of silybin, silydianin and silychristin, collectively known as silymarin.
Cosmate®SM,Silymarin 80%, a milk thistle extract standardized to 80% silymarin, an active compound noted for its antioxidant properties.
Silymarin is a flavonoid complex extracted from the seeds of the milk thistle plant (Silybum marianum). It is composed of several active compounds, including silybin, silydianin, and silychristin, with silybin being the most potent. Silymarin is renowned for its antioxidant, anti-inflammatory, and skin-protective properties. It is widely used in skincare to combat oxidative stress, soothe irritation, and support skin repair. Its ability to protect against UV-induced damage and promote collagen synthesis makes it a valuable ingredient in anti-aging and protective skincare formulations.
Silymarin Key Functions
Antioxidant Protection:Silymarin neutralizes free radicals caused by UV radiation and environmental pollutants, preventing oxidative damage and premature aging.
Anti-Inflammatory Effects:Silymarin reduces redness, swelling, and irritation, making it suitable for sensitive or inflamed skin.
UV Damage Protection:Silymarin helps mitigate the harmful effects of UV exposure, including photoaging and DNA damage.
Collagen Synthesis Support:Promotes collagen production, improving skin elasticity and reducing the appearance of fine lines and wrinkles.
Skin Barrier Repair:Silymarin enhances the skin’s natural barrier function, improving hydration and resilience.
Silymarin Mechanism of Action
Silymarin works by scavenging free radicals and reducing oxidative stress through its potent antioxidant activity. It inhibits inflammatory pathways, such as NF-κB and COX-2, to reduce redness and irritation. Additionally, silymarin protects skin cells from UV-induced damage by preventing DNA degradation and collagen breakdown. It also stimulates collagen synthesis and supports the skin’s natural repair processes, enhancing barrier function and overall skin health.
Silymarin Benefits and Advantages
Multifunctional:Silymarin combines antioxidant, anti-inflammatory, and anti-aging benefits in a single ingredient.
UV Protection:Silymarin provides additional defense against UV-induced damage, complementing sunscreen efficacy.
Suitable for Sensitive Skin:Gentle and non-irritating, making Silymarin ideal for reactive or inflamed skin.
Natural Origin:Silymarin derived from milk thistle, aligning with consumer preferences for plant-based and sustainable ingredients.
Stable Formulation:Compatible with a wide range of skincare products, including serums, creams, and sunscreens.
Technical Parameters:
Appearance |
Amorphous Powder |
Colour |
Yellow to Yellowish-Brown |
Odour |
Slight, Specific |
Solubility |
|
- in Water |
Practically Insoluble |
- in Methanol and Acetone |
Soluble |
Identification |
|
Sulphated Ash |
NMT 0.5% |
Heavy metals |
NMT 10 PPM |
- Lead |
NMT 2.0 PPM |
- Cadmium |
NMT 1.0 PPM |
- Mercury |
NMT 0.1 PPM |
- Arsenic |
NMT 1.0 PPM |
Loss On Drying (2 Hours 105 ℃) |
NMT 5.0% |
Powder size |
|
Mesh 80 |
NLT100% |
Assay of Silymarin (UV test, per cent, Standard in House) |
Min. 80% |
Residual Solvents |
|
- N-hexane |
NMT 290 PPM |
- Acetone |
NMT 5000 PPM |
- Ethanol |
NMT 5000 PPM |
Pesticide Residues |
USP43<561> |
Microbiological Quality (Total viable aerobic count) |
|
- Bacteria, CFU/g, not more than |
103 |
- Moulds and yeasts, CFU/g, not more than |
102 |
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
Applications:
*Antioxidant
*Anti-inflammatory
*Brightening
*Wound Healing
*Anti-photoaging
*Factory Direct Supply
*Technical Support
*Samples Support
*Trial Order Support
*Small Order Support
*Continuous Innovation
*Specialize in Active Ingredients
*All Ingredients are Traceable