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Sodium Acetylated Hyaluronate

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Cosmate^®AcHA,Sodium Acetylated Hyaluronate (AcHA), is a specialty HA derivative which is synthesized from the Natural Moisturizing Factor Sodium Hyaluronate (HA) by acetylation reaction. The hydroxyl group of HA is partially replaced with acetyl group. It owns both lipophilic and hydrophilic properties. This helps to promote high affinity and adsorption properties for the skin.

Trade Name: Cosmate®AcHA

Product Name: Sodium Acetylated Hyaluronate

INCI Name: Sodium Acetylated Hyaluronate

Molecular Formula: （C14H16O11NNaR4）n R=H or CH3CO

CAS No.: 158254-23-0

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Cosmate^®AcHA,Sodium Acetylated Hyaluronate (AcHA), is a specialty HA derivative which is synthesized from the Natural Moisturizing Factor Sodium Hyaluronate (HA) by acetylation reaction. The hydroxyl group of HA is partially replaced with acetyl group. It owns both lipophilic and hydrophilic properties. This helps to promote high affinity and adsorption properties for the skin.

Cosmate^®AcHA,Sodium Acetylated Hyaluronate (AcHA)is a derivative of Sodium Hyaluronate,which is prepared by acetylation of Sodium Hyaluronate,it is both hydrophilicity and lipophilicity.Sodium Acetylated Hyaluronate has the advantage of high skin affinity,efficient and lasting moisturing,softening stratum corneum,strong skin softening,enhancing skin slasticity,improving sin roughness,etc.It’s refreshing and non-greasy,and can be widely used in cosmetics such as lotion,mask and essence.

Cosmate^®AcHA,Sodium Acetylated Hyaluronate with below outstanding advantages:

High Skin affinity:Sodium Acetylated Hyaluronate hydrophilic and fat-friendly nature give it a special affinity with skin’s cuticles.The high skin affinity of AcHA makes it more evently and closely adsorbed on the surface of the skin,even after rinsing with water.

Strong Moisture Retention:Sodium Acetylated Hyaluronate can firmly adhere to the surface of the skin,reduce the loss of water on the skin surface,and increase the content of moisture of skin.It also can quickly penetrate into the stratum corneum,combine with the water in the stratum corneum,and hydrate to soften the stratum corneum.AcHA internal and external synergistic effect,play an efficient and lasting moisturing effect,increase skin water content,improve skin rough,dry state,make skin full and moist.

Technical Parameters:

Appearance	White to yellowish granule or powder
Acetyl Content	23.0~29.0%
Transparency(0.5%,80% Ethnol)	99% min.
pH(0.1% in water solution)	5.0~7.0
Intrinsic Vicosity	0.50~2.80 dL/g
Protein	0.1%max.
Loss on Drying	10% max.
Heavy Metals(As Pb)	20 ppm max.
Residue on Ignition	11.0~16.0%
Total Bacteria Count	100 cfu/g max.
Molds &Yeasts	50 cfu/g max.
Staphylococcus Aureus	Negative
Pseudomonas Aeruginosa	Negative