Cosmate® LUP ,Lupeol can inhibit the growth and induce apoptosis of leukemia cells. The inhibitory effect of lupeol on leukemia cells was related to the carbonylation of lupine ring.
Cosmate® LUP,Lupeol is a pentacyclic triterpene that has anti-inflammatory and antioxidant activity,that can be extracted from fruits and vegetables such as strawberry and mango as well as Chinese herbs and other plants. It has anti-inflammatory, antioxidant and wound healing pharmacological effects, and shows anti-cancer activity in pancreatic cancer, breast cancer, prostate cancer, melanoma and other tumors.
Lupeol is a naturally occurring triterpenoid found in various plants, including mango, olive, and shea butter. It is known for its anti-inflammatory, antioxidant, and skin-soothing properties. Lupeol is widely used in skincare for its ability to reduce irritation, protect against oxidative stress, and support skin repair. Its compatibility with the skin’s natural barrier and its multifunctional benefits make it a valuable ingredient in formulations targeting sensitive, aging, or damaged skin.
Key Functions
- Anti-Inflammatory Effects: Reduces redness, swelling, and irritation, making it ideal for sensitive or inflamed skin.
- Antioxidant Protection: Neutralizes free radicals caused by UV exposure and environmental pollutants, preventing oxidative damage and premature aging.
- Skin Barrier Support: Enhances the skin’s natural barrier function, improving hydration and resilience.
- Wound Healing: Promotes skin repair and regeneration, making it suitable for damaged or aging skin.
- Anti-Aging Benefits: Helps reduce the appearance of fine lines and wrinkles by protecting collagen and elastin fibers.
Mechanism of Action
Lupeol works by inhibiting inflammatory pathways, such as NF-κB and COX-2, to reduce redness and irritation. It also acts as a potent antioxidant, scavenging free radicals and preventing oxidative stress. Additionally, lupeol supports the skin’s natural repair processes by promoting collagen synthesis and enhancing barrier function. Its ability to regulate lipid production helps maintain skin hydration and elasticity.
Advantages
- Multifunctional: Combines anti-inflammatory, antioxidant, and anti-aging benefits in a single ingredient.
- Skin Compatibility: Naturally compatible with the skin’s lipid barrier, making it suitable for all skin types, including sensitive skin.
- Natural Origin: Derived from plant sources, aligning with consumer preferences for sustainable and eco-friendly ingredients.
- Non-Irritating: Gentle and well-tolerated, making it ideal for use in products for reactive or inflamed skin.
- Versatile Formulation: Compatible with a wide range of skincare products, including serums, creams, and soothing treatments.
Applications
- Soothing Creams: Calms redness and irritation in sensitive or inflamed skin.
- Anti-Aging Products: Reduces fine lines and wrinkles by protecting collagen and elastin fibers.
- Repair Serums: Supports skin barrier repair and hydration in post-procedure or damaged skin treatments.
- Daily Moisturizers: Improves overall skin health and resilience while protecting against environmental stressors.
- Cleansers: Maintains the skin’s natural lipid balance while gently cleansing.
Technical Parameters:
| Appearance | White powder |
| Purity(HPLC) | 98% min. |
| Particle-size | NLT100% 80 Mesh |
| Loss on drying |
2% max. |
| Heavy metal |
10 ppm max. |
| Lead |
2ppm max. |
| Mercury |
1 ppm max. |
| Cadmium |
0.5 ppm max. |
| Total number of bacteria |
1,000cfu/g max. |
|
Total Yeast & Mold |
100cfu/g max. |
|
Escherichia coli |
Not included |
|
Salmonella |
Not included |
|
Staphylococcus |
Not included |
Applications:
*Anti-inflammatory
*Skin Whitening
*Antioxidant
*Factory Direct Supply
*Technical Support
*Samples Support
*Trial Order Support
*Small Order Support
*Continuous Innovation
*Specialize in Active Ingredients
*All Ingredients are Traceable
