multi-functional,biodegradable biopolymer moisturizing agent Sodium Polyglutamate,Polyglutamic Acid

Sodium Polyglutamate

Short Description:

Cosmate^®PGA,Sodium Polyglutamate,Gamma Polyglutamic Acid as a multifunctional skin care ingredient,Gamma PGA can moisturize and whiten skin and improve skin health.It busilds gentle and tender skin and restore skin cells,facilitates exfoliation of old keratin.Clears stagnant melanin and gives birth to white and translucent skin.

Trade Name: Cosmate®PGA

Product Name: Sodium Polyglutamate

INCI Name: Sodium Polyglutamate

Molecular Formula: (C5H7NO3)n

CAS No.: 25513-46-6

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Cosmate® PGA, a cutting-edge biopolymer known as sodium polyglutamate or gamma-polyglutamic acid (γ-PGA). This naturally occurring, versatile, biodegradable compound is produced by fermentation of glutamic acid by Bacillus subtilis. Composed of glutamic acid monomers cross-linked by α-amino and γ-carboxyl groups, Cosmate® PGA is water-soluble, edible, and non-toxic, making it safe and environmentally friendly for human use. Its versatile properties make it ideal for a variety of applications including pharmaceuticals, food, cosmetics, and water treatment. Embrace innovation with Cosmate® PGA to provide sustainable, effective solutions for a variety of industries.

More Information about Cosmate^®PGA,Sodium Polyglutamate,Gamma Polyglutamic Acid

Cosmate® PGA, an innovative natural multifunctional biopolymer derived from sodium polyglutamate. Originally found in the traditional Japanese delicacy “Natto”, Cosmate® PGA is produced through a fermentation process utilizing Bacillus subtilis. Its water solubility makes it a unique homopolymer composed of D-glutamic acid and L-glutamic acid monomers bound via an amide bond between the α-amino and γ-carboxyl groups. This multifunctional ingredient has the potential to enhance a wide range of applications, offering significant benefits to the cosmetic, pharmaceutical and food industries due to its hydration, film-forming and bioadhesive capabilities. Embrace the natural excellence of Cosmate® PGA in your formulations.

Lage number of Carboxyl Groups along the molecule chain of Cosmate^®PGA can form hydrogen bonding in a molecule or between different molecules.Thus it has high water absorbability and moisture retaining capability.Thanks to its unique properties,

Gamma PGA can be used as thickener,filmogen,humcctant,retarder,cosolvent,binder and anti-freezer,therefore,the application prospect of Gamma PGA is promising.

Long-lasting Moisturization:With strong moisturizing ability, the side chain of Cosmate^®PGA can enhance the moisturizing capability of skinwithout breaking moisture balance of skin. When integrated into skin care products, Cosmate^®PGA can strengthen the moisturizing ability of skin and prevent skin from drying.

The higher the molecule weight, the stronger the winding effect between molecules. As the molecule network becomes larger, a Cosmate^®PGA elastic film will form on the surface of skin.Due to its unique molecule structure, gamma PGA(HM) can absorb and retain skin moisture efficientlyand form a silky film on the surface of skin.It can effectively prevent the skin from long-time drying condition, especially in air-conditioned rooms or in cold dry winter. Cosmate^®PGA enhances skin smoothness, reduces wrinkles and improves elasticity of skin.

The compound of Cosmate^®PGA (HM) and Cosmate^®PGA (LM) has better moisturizing efficacy. Cosmate^®PGA (HM) can form a protective film on the surface of skin to prevent loss of moisture. Meanwhile, Cosmate^®PGA (LM) can nourish skin to deep layer by locking more moisture and nutrients.

Synergy Effect:Moisture is a key factor to keep the skin healthy. Cosmate^®PGA can not only efficiently increase the moisture of skin, but participate in the metabolic activity of skin to improve the health condition of skin.

Increasing and Maintaining HA of Skin:As a basic component of skin, Hyaluronic Acid (HA) can lock the moisture of the skin and maintain its elasticity,but HA can hydrolyzed very quickly by hyaluronidase of skin as well, Cosmate^®PGA can increase and maintain the content of HA.

Effectively Increasing NMF in Inner Skin:As a hygroscopic material produced by skin, Natural Moisturizing Factor (NMF) provides moisture for skin in cuticle. The NMF including amino acids which are hydrolyzed fromskin matrix protein (e.g.Filament aggregating protein), pyrrolidone carboxylic acid (PCA), lactic acid and urocanic acid (UCA)can retain moisture of skin.Cosmate^®PGA is the only effective ingredient that is known till now to induce the production of NMF to 130% of the normal level. Cosmate^®PGA can lock the moisture in inner skin by promoting the growth of fibroblast and increasing the content of NMF in horn cells.

Improving Nutrient Supply:Thanks to its controlled release property, Cosmate^®PGA can control the release of nutrients and moisture in a continuous manner. Each Cosmate^®PGA monomer has ionized groups like α-COOH, -CO and -NH,which can absorb electropositive nutrients. Hence a good embedding deliverysystem is created and active ingredients in cosmetics can possibly maximize their efficacy

Healthy Whitening Efficacy:Cosmate^®PGA can also whiten skin by controlling melanin synthesis to prevent and reduce freckles.Ultraviolet irradiation is the main incentive of tyrosinase, which in tum induces the formation of Melanin.

Technical Parameters:

Appearance	White to off-white powder or granules
Assay	92% min.
pH(1% Solution)	5.0~7.5
Instrinsic Viscosity	1.0Dl/g (or as requested)
Absorbance(4%,400nm)	0.12 max.
Heavy Metals	10 ppm max.
Loss on Drying	10% max.
Total Plate Count	100 cfu/g
Molds&Yeasts	100 cfu/g