Research and development of pyridoxine tripalmitate
Pyridoxine Tripalmitate is a B6 derivative of vitamin B6, which completely retains the activity and corresponding efficacy of vitamin B6. Three palmitic acids are connected to the basic structure of vitamin B6, which changes the original water-soluble property to lipophilic and lipophilic properties, thereby improving absorption and stability. Studies have shown that pyridoxine tripalmitate has good skin penetration properties, can effectively increase the skin absorption rate and accumulation of pyridoxine, and enhance its bioavailability in skin tissue [1]. In vitro experiments have also confirmed that pyridoxine tripalmitate can promote collagen synthesis and inhibit matrix metalloproteinases, achieving moisturizing, anti-wrinkle and anti-aging effects.
Efficacy evaluation of pyridoxine tripalmitate
1. Skin care
It can inhibit pigmentation and keep skin white. Its anti-inflammatory and collagen synthesis functions can also moisturize the skin and avoid dry and cracked skin caused by deficiency. Regulates the activity of sebaceous glands and can be used as a skin oil control product.
2. Hair care
One of the most prominent functions is to protect hair and prevent it from falling out. It plays a key role in the process of new hair growth from hair follicles. When the body lacks B6, a common symptom is seborrheic dermatitis of the scalp, which can seriously cause hair loss.
The reason is that hair growth requires hair follicle mother cells to synthesize sulfur amino acids, and this process requires the participation and catalysis of vitamin B6. If it is insufficient, hair follicle cells cannot grow hair smoothly, the hair growth cycle is forced to shorten, and it is easy to fall off [2].
Seborrheic dermatitis can also aggravate inflammation of hair follicles, causing hair to become brittle and breakable. Therefore, sufficient vitamin B6 derivative-pyridoxine tripalmitate is extremely important to ensure normal hair follicle growth and hair health. It prevents hair loss and also improves seborrheic scalp problems.
Applications of pyridoxine tripalmitate
Pyridoxine tripalmitate is a liposomal derivative of vitamin B6. It connects three palmitic acid groups to the pyridoxine molecule, so vitamin B6, which is originally more water-soluble, becomes lipophilic and lipophilic.
This structural design greatly enhances the oil solubility and lipophilicity of pyridoxine tripalmitate. It is oil- and water-soluble and is more soluble in fats and oily matrices. This not only improves its affinity to the lipid cell membrane, but also makes it easier to penetrate skin tissue and be absorbed by the skin.
At the same time, the addition of lipophilic groups also enhances the stability of pyridoxine tripalmitate, avoiding the shortcomings of ordinary water-soluble vitamin B6 being easily hydrolyzed and losing activity. Therefore, the bioavailability and skin care effect of pyridoxine tripalmitate are better than those of vitamin B6 itself.
Post time: Mar-08-2024
