Quots for CAS 22888-70-6 Milk Thistle Seed Extract Powder 80% Silymarin

Silymarin

Short Description:

Cosmate®SM, Silymarin refers to a group of flavonoid antioxidants that naturally occur in milk thistle seeds (used historically as an antidote for mushroom poisoning). The components of Silymarin are Silybin, Silibinin, Silydianin, and Silychristin. These compounds protect and treat the skin from oxidative stress caused by ultraviolet radiation. Cosmate®SM, Silymarin also has powerful antioxidant properties that prolong cell life. Cosmate®SM, Silymarin can prevents UVA and UVB exposure damage. It is also being studied for its ability to inhibit tyrosinase (a critical enzyme for melanin synthesis) and hyperpigmentation. In wound healing and anti-aging, Cosmate®SM,Silymarin can inhibit the production of inflammation-driving cytokines and oxidative enzymes. It can also increase collagen and glycosaminoglycans (GAGs) production, promoting a broad spectrum of cosmetic benefits. This makes the compound great in antioxidant serums or as a valuable ingredient in sunscreens.

Trade Name: Cosmate®SM

Product name: Silymarin

INCI Name: Silybum marianum extract

Molecular Formula: C25H22O10

CAS No.: 65666-07-1

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Cosmate®SM, Silymarin, a natural flavonoid lignan compound, is extracted from the dried fruit of milk thistle, a plant in the asteraceae family. Its main components are silybin, isosilybin, silydianin and silychristin. Cosmate®SM,Silymarin is insoluble in water, easily soluble in acetone, ethyl acetate, methanol ethanol, slightly soluble in chloroform.

For over 2,000 years Silybum marianum has been working its magic. Ancient Greeks and Romans used Milk Thistle against the venom of snake bites, today Milk Thistle’s phyto-compounds are translated through cosmetics, body products, serums and haircare. The NE Milk Thistle Cellular Extract’s phyto-compounds may be considered for numerous skin conditions, hydration, pollution defense, fine lines, wrinkles and more. The NE Milk Thistle Cellular Extract delivers the highest concentration of silymarin, believed to have powerful healing powers, as well as tryptophan, and amino and phenolic acids.

Cosmate®SM, Silymarin 80% is well known as a potent herb for liver disorders. The active ingredients in milk thistle are flavonoids comprised of silybin, silydianin and silychristin, collectively known as silymarin.

Cosmate®SM,Silymarin 80%, a milk thistle extract standardized to 80% silymarin, an active compound noted for its antioxidant properties.

Technical Parameters:

Appearance	Amorphous Powder
Colour	Yellow to Yellowish-Brown
Odour	Slight, Specific
Solubility
- in Water	Practically Insoluble
- in Methanol and Acetone	Soluble
Identification	Thin-Layer Chromatographic Identification Test HPLC Identification Test
Sulphated Ash	NMT 0.5%
Heavy metals	NMT 10 PPM
- Lead	NMT 2.0 PPM
- Cadmium	NMT 1.0 PPM
- Mercury	NMT 0.1 PPM
- Arsenic	NMT 1.0 PPM
Loss On Drying (2 Hours 105 ℃)	NMT 5.0%
Powder size
Mesh 80	NLT100%
Assay of Silymarin (UV test, per cent, Standard in House)	Min. 80%
Residual Solvents
- N-hexane	NMT 290 PPM
- Acetone	NMT 5000 PPM
- Ethanol	NMT 5000 PPM
Pesticide Residues	USP43<561>
Microbiological Quality (Total viable aerobic count)
- Bacteria, CFU/g, not more than	10³
- Moulds and yeasts, CFU/g, not more than	10²
- E.coli, Salmonella, S. aureus, CFU/g	Absence