Ethylbisiminomethylguaiacol Manganese Chloride

Cosmate®EUK-134 is a new product developed based on SOD. As a small molecule compound, EUK-134 can directly enter the skin and exert its effects, solving the problem of large SOD molecules and poor stability. As one of the raw materials for cosmetics, EUK-134 has dual activity and can eliminate superoxide radicals. It has the effects of brightening the skin, improving oily skin, alleviating skin inflammation, and maintaining skin transparency and whiteness. It also has regenerative ability and stability better than SOD and CAT. Based on its strong antioxidant and regenerative properties, EUK-134 will be increasingly used in fields such as anti-aging cosmetics, sun protection cosmetics, whitening cosmetics, and skin repair products.

EUK-134 (Ethylbisiminomethylguaiacol Manganese Chloride) is a synthetic, small-molecule antioxidant that mimics the activity of superoxide dismutase (SOD) and catalase, two of the body’s most powerful natural antioxidant enzymes. It is widely used in skincare formulations to protect the skin from oxidative stress, reduce signs of aging, and enhance overall skin health. Its unique dual-enzyme activity makes it a standout ingredient in advanced anti-aging and protective skincare products.

Key Functions

1. Antioxidant Protection: Neutralizes free radicals generated by UV radiation, pollution, and other environmental stressors, preventing oxidative damage.
2. Anti-Aging Benefits: Reduces the appearance of fine lines, wrinkles, and age spots by protecting collagen and elastin from degradation.
3. DNA Repair Support: Helps repair DNA damage caused by UV exposure, reducing the risk of long-term skin damage.
4. Skin Soothing: Calms inflammation and redness, making it suitable for sensitive or irritated skin.
5. Photoprotection: Enhances the skin’s natural defense mechanisms against UV-induced damage.

Mechanism of Action

1. Superoxide Dismutase (SOD) Mimicry: Converts superoxide radicals into hydrogen peroxide and oxygen, neutralizing harmful free radicals.
2. Catalase Mimicry: Breaks down hydrogen peroxide into water and oxygen, preventing oxidative stress and cellular damage.
3. DNA Repair Activation: Supports the repair of UV-induced DNA damage, reducing the risk of mutations and premature aging.
4. Collagen Protection: Prevents the breakdown of collagen and elastin by inhibiting oxidative stress and matrix metalloproteinases (MMPs).
5. Anti-Inflammatory Effects: Reduces inflammation and redness by modulating inflammatory pathways.

Advantages

1. Dual-Action Antioxidant: Combines the activities of SOD and catalase for comprehensive antioxidant protection.
2. High Stability: Remains effective in formulations, even under challenging conditions like exposure to light and air.
3. Proven Efficacy: Clinically tested and proven to reduce signs of aging and protect against environmental damage.
4. Gentle on Skin: Suitable for all skin types, including sensitive skin, with minimal risk of irritation.
5. Versatile: Compatible with a wide range of formulations, including serums, creams, lotions, and sunscreens.

Applications

1. Anti-Aging Skincare: Ideal for serums, creams, and masks targeting wrinkles, fine lines, and loss of elasticity.
2. Daily Defense Products: Perfect for day creams and lotions that protect the skin from environmental stressors like pollution and UV radiation.
3. Sun Care Formulations: Enhances the protective effects of sunscreens by providing additional antioxidant support.
4. Post-Procedure Care: Suitable for products designed to soothe and repair skin after cosmetic procedures or sun exposure.
5. Luxury Skincare: Often used in premium anti-aging and protective skincare lines due to its high efficacy and innovative mechanism.

Technical Parameters:

Antioxidant mechanism

Antioxidant mechanism:through the redox cycle of Mn(II),the superoxide anion(o2) is converted into peroxide(H2O2),and then the hydrogen    peroxide is converted into water(H2O)

Effectively and repair UV induced by DNA mutation

Thymine dimer(TT dimer) is a pair of abnormally chemically bonded thymine bases in DNA ,which is caused by the damage triggered by ultraviolet radiation.Skin exposure to ultraviolet light can lead to cross-linking of thymine in DNA.

Effectively reduce erythema and lipid peroxidation caused by ultraviolet light;repair damage

Applications:

*Antioxidant

*Skin whitening

*Antioxidation

*Factory Direct Supply

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*Continuous Innovation

*Specialize in Active Ingredients

*All Ingredients are Traceable