Cosmate®ZnPCA,Zinc PCA is a water-soluble zinc salt that is derived from PCA, a naturally occurring amino acid that is present in the skin.It’s a combination of zinc and L-PCA, helps regulate the activity of the sebaceous glands and reduces the level of skin sebum in vivo. Its action on bacterial proliferation, notably on Propionibacterium acnes, helps limit the resulting irritation.