Zinc PCA (PCA-Zn) CAS 15454-75-8 for Acne Treatments

Zinc Pyrrolidone Carboxylate

Short Description:

Cosmate®ZnPCA,Zinc PCA is a water-soluble zinc salt that is derived from PCA, a naturally occurring amino acid that is present in the skin.It’s a combination of zinc and L-PCA, helps regulate the activity of the sebaceous glands and reduces the level of skin sebum in vivo. Its action on bacterial proliferation, notably on Propionibacterium acnes, helps limit the resulting irritation.


  • Trade Name: Cosmate®ZnPCA
  • Product Name: Zinc Pyrrolidone Carboxylate
  • INCI Name: Zinc PCA
  • Molecular Formula: C10H10N2O6Zn
  • CAS No.: 15454-75-8/ 68107-75-5
  • Product Detail

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    Cosmate®ZnPCA,Zinc Pyrrolidone Carboxylate,Zn PCA,Zinc PCA,Zn-PCA,is the Zinc salt of pyrrolidone carboxylic acid, is a zinc ion in which sodium ions are exchanged for bacteriostatic action,a synthetic skin-conditioning ingredient derived from zinc that has anti-aging benefits due to its ability to suppress collagenase, an enzyme that, left unchecked, breaks down healthy collagen in skin.It also acts as a humectant, UV-filter, antimicrobial, anti-dandruff, refreshing, anti-wrinkle and moisturizing agent.

    Cosmate®ZnPCA regulating sebum production: It inhibits the release of 5α- reductase effectively and regulates   sebum production.Cosmate®ZnPCA suppresses propionibacterium acnes. lipase and oxidation. so it decreases stimulation; reduces inflammation and prevents acne production. which makes it multiple conditioning effect of suppressing free acid. avoiding inflammation and regulating oil levels Zinc PCA  is widely touted as a standout skincare ingredient that effectively addresses issues such as dull appearance, wrinkles, pimples, blackheads.

    Cosmate®ZnPCA can improve sebum secretion, regulate sebum secretion, prevent pore blockage, maintain oil-water balance, mild and non-irritating skin and no side effects.The Zn element contained in it has good anti-inflammatory effect, effectively preventing acne and anti-bacterial and fungal. The oily skin type is a new ingredient in the physiotherapy lotion and conditioning liquid, which gives the skin and hair a soft, refreshing feeling. It also has anti-wrinkle function because it inhibits the production of collagen hydrolase. It is suitable for oily skin and acne skin cosmetics, conditioning skin to dandruff, applying acne cream, make-up, shampoo, body lotion, sunscreen, repair products and so on.

    Technical Parameters:

    Appearance White or off-white powder
    pH Value(10% in aqueous solution) 5.0~6.0
    PCA Content(on dry basis) 78.3~82.3%
    Zn Content 19.4~21.3%
    Water 7.0% max.
    Heavy Metals 20 ppm max.
    Arsenic(As2O3) 2 ppm max.

    Applications:

    *Preservatives

    *Moisturizing Agent

    *Sunscreen

    *Anti-dandruff

    *Anti-Aging

    *Anti-Microbials

    *Anti-acne


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